Vacina em 'spray', aplicada pelo nariz, é aposta contra covid-19

Há pelo menos 100 tipos de vacinas em desenvolvimento no mundo, diz OMS Dado Ruvic/Reuters - 10.4.2020

A USP (Universidade de São Paulo) trabalha no desenvolvimento de uma vacina por spray nasal contra a covid-19, infecção respiratória provocada pelo novo coronavírus (SarS-Cov-2).

O método, que já foi testado em camundongos contra a hepatite B, deve passar por novos testes em animais em setembro. Ainda não há previsão para a aplicação de doses em seres humanos.

Segundo o coordenador do estudo, Marco Antonio Stephano, da FCF (Faculdade de Ciências Farmacêuticas), a expectativa é que o imunizante, elaborado por meio da inclusão de uma proteína do vírus, seja capaz de estimular a produção de anticorpos IgA secretora —presentes, por exemplo, na saliva.

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A partícula criada pelo grupo de pesquisadores é composta por uma “propriedade muco adesiva”, que seria capaz de permanecer nas narinas tempo suficiente para que o imunizante seja absorvido pelo organismo e, assim, possa ativar a resposta contra a infecção.

O grupo é composto por virologistas e imunologistas do Instituto de Ciências Biomédicas, pesquisadores da Plataforma Científica Pasteur-USP, da Unicamp, especialistas em nanotecnologia do Instituto de Química da USP e, também, uma startup.

Se aprovada após todas as etapas de testes, a expectativa é que a vacina chegue ao público a um custo de aproximadamente R$ 100.

Este texto foi publicado primeiro em http://noticias.r7.com/tecnologia-e-ciencia/vacina-em-spray-aplicada-pelo-nariz-e-aposta-contra-covid-19-05062020

Via RSS publicado em https://vitorolig.tumblr.com/post/620152875330453504

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