Covid-19: Remdesivir tem resultados mistos em teste com doentes

Estudo com medicamento está em fase final Gilead Sciences Inc/Reuters

A empresa farmacêutica Gilead Sciences disse nesta segunda-feira (1º) que o remédio antiviral ‘remdesivir’ apresentou resultados mistos em um estudo de fase final com pacientes de covid-19 em estágio moderado, já que as pessoas que receberam um tratamento de cinco dias apresentaram melhora estatisticamente significativa, enquanto aqueles que receberam por 10 dias, não.

O remdesivir está sendo observado após a FDA (Administração de Alimentos e Medicamentos) dos Estados Unidos conceder aval de uso de emergência no mês passado, citando resultados de outro estudo realizado pelo National Institutes of Health, que mostrou que o medicamento reduziu o tempo de internações de pacientes em 31%, ou cerca de quatro dias, na comparação com um placebo.

O remdesivir, que falhou antes como tratamento para o ebola, foi projetado para desativar o mecanismo pelo qual certos vírus, incluindo o coronavírus, se reproduzem e potencialmente sobrecarregam o sistema imunológico de seus hospedeiros.

Os resultados anunciados por Gilead hoje são de um estudo desenvolvido para avaliar a segurança e eficácia do tratamento de 5 e 10 dias com o remdesivir, juntamente com o tratamento padrão para pacientes com Covid-19 moderado, em comparação com apenas o tratamento padrão.

No dia 11, mais pacientes no grupo de tratamento de 5 dias apresentaram melhora no estado clínico em relação ao grupo de tratamento padrão, disse a Gilead.

A farmacêutica disse que as chances de melhora com o tratamento de 10 dias do remdesivir contra o tratamento padrão também eram favoráveis, se aproximando, mas não alcançando uma significância estatística.

Este texto foi publicado primeiro em http://noticias.r7.com/tecnologia-e-ciencia/covid-19-remdesivir-tem-resultados-mistos-em-teste-com-doentes-01062020

Via RSS publicado em https://vitorolig.tumblr.com/post/619775393327611904

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